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Department of Experimental Medicine

  • The Department of Experimental Medicine (DEM) is the first department to be started in the Medical University in the year 1992. Its focus has been on infectious diseases and mainly on HIV/AIDS and Leptospirosis. The Department is involved in multidisciplinary research to address the challenging issues that are relevant to the society. The department has proved its excellence at both national and international level in education and research in HIV and Leptospirosis. This department was the first in the country to provide rural PMTCT (Prevention of Mother to Child Transmission of HIV) services from the year 2000 onward at Namakkal District, Tamilnadu. In the year 2009 the department has been recognized as a Referral Laboratory for HIV DNA PCR testing by National AIDS Control Organization (NACO), Government of India. The Department is also recognized as a National Reference Laboratory (NRL) for HIV testing under the External Quality Assessment Scheme (EQAS) of NACO since the year 2000.

    The Department's activities involve

    • Education and Training
    • Research Programs
    • Diagnostic Services
    • National Reference Center for HIV/AIDS
    • Implementation of MTCT program at rural areas of Tamilnadu.

    Faculty

    • Dr S. Mini Jacob, MD., Professor & HOD  [Read More]
    • Dr .K.Sivasangeetha, MD., Associate Professor  [Read More]

    Staff

    • Dr. K. Mary Sushi, M.Sc, M.Phil, Ph.D. (Research Officer)  [Read More]
    • Dr. D. Anitha, M.Sc,M.Phil., Ph.D., (Research Officer)  [Read More]
    • Mr. G .Thatchinamoorthy, B.Sc,DMLT, M.Sc. (Lab Technician Gr1 )
    • Mr. A .Ganesan, M.Sc,M.Phil (Research Officer)
    • Mr. V .Mohan, (Lab Technician Gr III)
    • Ms .R. Vanitha, (Lab Technician Gr III)
    • Mr. G . Pachaiappan, (Lab Technician Gr III)

    Workshops, Training program and conferences attended by the staff of the Department

      • 2012

      • Dr.S. Mini Jacob conducted the Ethical Committee meeting on 13/6/12.
      • Dr. Mary Sushi attended the NRL review meet at NARI, Pune on 25th January, 2012.
      • Dr. S. Mini Jacob attended the International workshop on HIV/AIDS and women in Washington DC (January 9th to 13th 2012).
      • Ms. Baby and Mr. Rajkumar (laboratory technician) attended the ICTC Lab Technician Training program held at Stanley Medical College from 3rd to 7th January 2012.

      • 2011

      • Dr. Mary Sushi attended the HIV/AIDS update at TB Sanatorium Hospital from 14th to 16th November, 2011.
      • Mr.Pachiappan & Ms. Vanitha attended the Biosafety and calibration of Equipments workshop held at the Microbiology Department in Madras Medical College from 5th to 7th August, 2011.
      • Ms.Anitha & Dr.Mary Sushi attended the Biosafety workshop of MMC/ TANSAC on 14th & 15th of July, 2011.
      • Mr.Ganesh & Mr.Thatchinamoorthy attended the Calibration of Equipments and Biomedical waste training program from May 30 to 1st June, 2011 at TB Sanatorium Hospital.
      • Mr.Thatchinamoorthy attended a training program on filter paper testing of sentinel surveillance samples at NARI on 7 & 8th of April, 2011.
      • Ms.Anitha attended the Introduction and Scientific and Medical writing workshop held in Epidemiology Department on 18/3/2011
      • Mr.S.Ganesan & Dr.K.Mary Sushi participated in the Scientific workshop conducted by ITECH and CDC in Chennai ( Feb 17 & 18th 2011)
      • Ms.Amudha & Dr.K.Mary Sushi participated in the SRL meeting held at TANSAC(29th January 2011)
      • Dr.S.Mini Jacob participated in the International workshop on HIV/AIDS and women in Washington,DC (January 10 & 11th 2011)

      • 2010

      • Dr Mini Jacob gave a lecture on “Testing related to HIV” for Medical officers participating in “NACO Training program for LACs (Linked ART Centers)" on 14th December, 2010 at GHTM training center, Tambaram Sanatorium.
      • Ms. Amudha attended the EQAS NARI training program held in October 2010.
      • Dr S Mini Jacob attended the HIV DNA PCR meeting held at Hyderabad on Sept 31 & October 1st, 2010 conducted by NACO, APSACS.
      • Ms. Anitha attended the HIV Science Symposium held at YRG Care in August 2010.
      • Mr Thatchinamoorthy, underwent HPLC training at C.L. Baid Mehta College of Pharmacy 12-17th July, 2010.
      • Mr Ganesan attended the EQAS training program at Pondicherry State AIDS Control Society on July 7-9th, 2010.
      • Ms Amudha of the EQAS project visited NARI, Pune and brought the coded samples from NARI to be tested in the Department on May 20th 2010
      • Dr S Mini Jacob participated at the “International Conference on Health System Strengthening” organized by the Tamilnadu Health System Project, Government of Tamil nadu from 6-10th May, 2010 at Mamallapuram, Chennai.
      • Dr S Mini Jacob attended the SRL meeting on NABL Certification conducted by NACO on 6th & 7th April 2010 in Bengaluru.
      • Dr S Mini Jacob attended Training on diagnosis of HIV in infants and children below 18 months by using DNA PCR Testing–The National Early Infant Diagnosis (EID) program of National AIDS Control Organization (NACO) 9th –11th February, 2010 at Hyderabad.
      • Dr S Mini Jacob attended the 'Apex Lab Meeting' under the EQAS program of NACO, conducted by National AIDS Research Institute (NARI), Pune on the 28th & 29th January 2010
      • Ms Amudha of the EQAS program attended the Training Program for Technical officers SRL from 21.01.2010 to 23.01.2010 at GHTM, Tambaram Sanatorium. Dr Mini Jacob gave a talk on “Introduction to HIV, Transmission and disease”
      • Dr Mini Jacob, Dr Mary Sushi and Ms Amudha attended the SRL review meeting at Tamilnadu State AIDS Control Society on 05/01/2010.
      • Mr. Ganesh Arumugam, Laboratory Technician underwent training in " Laboratory Management System and ISO-15189 internal audit for clinical laboratories" at Center for Electronics Test Engineering (CETE), Government of India, Bangalore from September 8-11th, 2009
      • Dr M.R. Sivakumar met with Dr Ann Melvin, Dr Thor Wagner and Mrs Nina Ellis at the University of Washington Seattle USA to discuss the Indo US Project on 28th of April, 2009.
      • Dr S Parameshwari, Dr S Mini Jacob and 2 medical students from the University of Washington (Ms Natalie and Ms Andrea) attended the Medical symposium on Pneunocystic Jeroveci Pneumonia organized by the ITECH Fellows at Tambaram Sanatorium on the 6th of April, 2009.
      • Mr G Thatchinamoorthy, Laboratory Technician and Dr S Mini Jacob attended one-week South Zone workshop on External Quality Assurance Scheme in NIMHANS Bangalore organized by the NACO on 27th April to May 1st, 2009
      • Dr S Mini Jacob attended a workshop on "Latest approach to HIV infection and management" conducted by Merieux Foundation on March 3-6th 2009 at New Delhi.
      • Mr. Ganesh Arumugam and Mr. G Thatchinamoorthy, Laboratory Technicians participated in the workshop for Dried Blood Spot testing under HIV sentinel surveillance held at National AIDS research Institute (NARI), Pune, on19th & 20th March 2009.
      • Dr M.R. Sivakumar, Prof & HOD was invited to speak on "NeuroAIDS" to ITECH fellows and visiting international ITECH faculty at Tambaram Sanatorium on 16th of February, 2009.
      • Dr S Mini Jacob gave a lecture on HIV Diagnosis to the ART Medical Officers at Tambaram Sanatorium on 10th of February, 2009.
      • Dr S Parameshwari attended the 2nd ASCCON Conference on HIV/AIDS which was held on 27th February to 1st March 2009 at Jaipur and presented a poster on PMTCT program.
      • Dr M. R Sivakumar, Prof & HOD and Dr S Mini Jacob attended the Training of the Trainers Program (Training on HIV/AIDS for the laboratory technicians of the Tamilnadu State AIDS Control Society) at the Department of Microbiology at the Madras Medical College on 6th October 2008.
      • Dr S Mini Jacob attended a clinical symposium on "2nd line regimen of ART" conducted by the ITECH Fellows at Tambaram Sanatorium on 17th of October, 2008.
      • Dr S Mini Jacob attended " External Assessment of HIV testing quality of NRL's with Apex Laboratory" in National Institute of Biologicals at Noida from 23-25th September 2008.
      • Scientists from NACO and CDC visited the department for the monitoring and evaluation of the Laboratory as well as for EQAS on the 16th July 2008.
      • Dr M. R Sivakumar Prof & HOD visited the Puget Sound Blood Center , Seattle USA on the 2nd week of June, 2008 to observe Umbilical Cord blood banking.
      • Dr.S.Mini Jacob, Ms.D.Anitha and Ms.K.Annie Phoebe attended the 3rd INTEREST Workshop at Lusaka, Zambia -May 2009.
      • Dr S Mini Jacob attended the 2nd INTEREST Workshop at Dakar, Senegal -May 2008.
      • Ms D Anitha, visited Department of Laboratory Medicine, University of Washington, Seattle, USA for training in HLA Typing assays-July 2008
      • Dr. K. Mary Sushi, Mr. G Thatchinamoorthy, Ms.Vijayakumari attended the HIV/STD Training program at University of Washington, Seattle, USA- July 2007.
      • Dr S Mini Jacob was trained to Perform P24 antigen assay at the Department of Pediatrics and Laboratory Medicine (under Dr. Lisa M Frenkel), University of Washington, Seattle, Washington, USA. May 13th –June 30th, 2006
      • Dr.Parameswari, Dr.S.Mini Jacob, Dr.S.Shoba and Dr.N.M.Samuel attended the Eighth International Congress on Drug Therapy in HIV Infection 12-16 November 2006 Glasgow, UK
      • Dr S Parameshwari attended the HIV/STD Training program at University of Washington, Seattle, USA- July,2005.
      • Mr A Ganesan attended training in Laboratory techniques in the Department of Pediatrics and Laboratory Medicine (under Dr. Lisa M Frenkel), University of Washington, Seattle, Washington, USA. July , 2005
      • Dr N M Samuel, Dr S Mini Jacob, Dr S Shoba and Ms JJ Vijayakumari attended the 3rd IAS Conference on HIV Pathogenesis and Treatment, Rio de Janeiro, Brazil, 24-28 July, 2005
      • Dr N. M. Samuel and Ms. D Anitha attended the XV International AIDS Conference 2004, July 11-14th, at Bangkok, Thailand.
      • Dr S Mini Jacob, underwent training in OligoNucleotide Ligation Assay (OLA) in Dr. Lisa Frenkel's Laboratory at the University of Washington for 8 weeks (July- September, 2004). As a part of the training program, she also participated in "Principles of STD/HIV Research" Course, held by the University of Washington, Center for AIDS and STD, Seattle, Washington, USA. July 19-29, 2004.
      • Dr.K.Mary Sushi and Ms.Vijayakumari attended the EGPAF Call to Action Directors Meeting at Kampala, Uganda October 11-14th, 2004.
      • Prof. Dr. C. V. Bhirmanandham and 3 faculty members and two Research Scholars of the Department attended and presented papers at The 2nd IAS Conference on HIV Pathogenesis and Treatment, Paris, France, 13-16 July, 2003.
      • Mr A Ganesan attended the Leptospira training program at the National Referral Center for Leptospirosis at ICMR, Port Blair, Andaman, 2003
      • Dr N. M Samuel, Dr S Mini Jacob and Ms Udayakumari participated in EGPAF Call to Action Site Directors meeting at Cape Town, South Africa in August 18-21st, 2003.
      • Dr.R Vishwanath and Ms. D Anitha were trained for a period of 8 weeks (October to December 2003) at University of Washington Seattle, USA for HIV resistance testing at Dr. Lisa Frenkel's Laboratory.
      • Ms.Vijayakumari and Dr.S.Mini Jacob participated in the workshop on Grant Writing organized by the Elizabeth Glaser Pediatric AIDS Foundation, USA at Mysore, Karnataka in January 2002.
      • Under the leadership of Prof. Dr. C. V. Bhirmanandham and four staff members of the Department attended the X1V International AIDS Conference-Barcelona, Spain, July, 2002.
      • Dr S Mini Jacob and Dr. R Vishwanath were trained in automated DNA Sequencing and HIV drug resistance testing at Center De Biologic, Madrid, Spain, 2002
      • Dr N M Samuel, attended the 1st International AIDS Society Conference on HIV pathogenesis and treatment held at Buenos Aires, Argentina – July 2001.
      • Dr N M Samuel attended the World Federation of Scientists, Erice, Italy on August 2001.
      • Dr N M Samuel attended the 3rd Conference on global strategies for the prevention of HIV transmission from Mother to Infants, Kampala, Uganda-September 2001.
      • Dr.R.Vishwanath, Dr S. Parameshwari and Dr.S.Mini Jacob attended the advance training on HIV Clinical Management organized by the International Antiviral Therapy Evaluation Center (IATEC) in collaboration with the Department of Internal Medicine and the Department of Virology, University of Amsterdam. The Netherlands from 1st June 2001 – 6th July 2001.
      • Dr.K.Mary Sushi attended and presented at the 6th International Congress on AIDS in Asia and the Pacific, Melbourne, Australia - October 2001.
      • Dr.S.Parameshwari attended the meeting on the development of Manual of Procedures for the MTCT project at the National Institute of Child Health Development, Washington, USA in November 2001.
      • Dr.S.Mini Jacob, Dr.K.Mary Sushi attended the SEAWP workshop on Quality Assurance in HIV testing at Bangkok, Thailand in February 2000.
      • Dr N M Samuel, Dr S Mini Jacob and Dr S Parameshwari attended 2nd Conference on Global Strategies for the prevention of HIV transmission from Mothers to Infants: Montreal, Canada, September 1999
      • Dr S Mini Jacob and Dr S Parameshwari attended Training programme on HIV/AIDS at the KIS clinic, Munich, Germany: June-July 1998
      • Dr Major D.Raja, Dr N.M Samuel, Dr S Mini Jacob and Dr S Parameshwari attended 12th World AIDS Conference, Geneva, Switzerland: July 1998
      • Dr S Mini Jacob, Dr S Parameshwari and Ms Adeline Attended seminar on role and responsibility of women for the prevention of RTI/STD/HIV/AIDS conducted by TANSACS, 1997
      • Mrs G Sundari and Dr S Mini Jacob underwent training in the use of HPLC (High Performance Liquid Chromatography) at the Nizam Institute of Medical Sciences, Hyderabad, September 1994
      • Dr. Mini Jacob trained in the use of HPLC-Course sponsored by Lab India at Pune, October, 1994

    Contact:
    Dr. S. Mini Jacob, MD.,
    Professor & HOD
    Department of Experimental Medicine,
    The Tamilnadu Dr MGR Medical University,
    No.69, Anna Salai, Guindy, Chennai-32
    Phone: 91 44 22300779
    Email ID : This email address is being protected from spambots. You need JavaScript enabled to view it.This email address is being protected from spambots. You need JavaScript enabled to view it.

  • Courses

    One year PG Diploma Course on HIV/AIDS has been sanctioned.

    Degree

    The Department has full-time and part-time research programs leading to Ph.D degrees. 5 Research Scholars have been awarded Ph.D Degrees. At present the Department has two part-time Research Scholars.

    International Conferences

    The Department conducted Five International Conferences on "AIDS India" in the years 1997, 1999, 2001, 2003 & 2005. Around 7500 health care workers attended the conferences. 300 International experts on HIV/AIDS delivered lectures and participated.

    Training/Workshops/Seminar

    2012

    • The following projects have been implemented/continued in the department in collaboration with National AIDS Control Organization and Tamil Nadu State AIDS Control Society,Early Infant Diagnosis testing of HIV exposed infants.External Quality Assurance Scheme (EQAS), Sentinal Surveillance of HIV
      Ms. Sumathy Quality Manager from TANSACS visited the department on 7th and 26th of September, 2012 to discuss regarding the funds for the above projects.
    • ISO surveillance audit was done for the Department on 17th September, 2012. Mr. Velumurugan and Mr. Karthick from IQ Management System inspected the department along with the ISO representative, Mr. Natarajan.
    • Dr. R. Viswanathan from FDA, Washington DC visited DEM on 6th &12 July, 2012 and discussed on the research aspects of HIV/AIDS.
    • The EQAS Round I workshop was held on 30/3/12.Panels were distributed.

    2011

    • The EQAS IInd workshop was held on 16/12/11. Eight coded samples for the SRLs and 4 coded samples were distributed for the ICTC and Blood banks.
    • Dr.Sunitha from CDC/NACO visited the Department regarding NABL certification on 22nd November, 2011.
    • The ISO Auditors visited and inspected the Department on 27th and 28th of June, 2011.
    • Dr.Goel from NACO visited Department on 18th April, 2011 and discussed regarding the testing in Sentinel Surveillance of HIV.
    • The NACO assessors (Dr.Ichapunchi, Dr.Lalitha and Dr.Nagendra ) visited the Department regarding NABL certification on 31/3/2011.
    • Dr. Joseph from National Institute of Epidemiology (NIE), Chennai visited the department for the Sentinel Surveillance program on 16th March, 2011
    • The staff members of the department participated in the ISO meeting held at Senate hall of the University in March 2011

    2010

    • The EQAS IInd workshop was held on 10/12/10. Panels were distributed to designated State Reference Laboratories.
    • The EQAS 1st workshop was held on 20/8/10.Panels were distributed to designated State Reference Laboratories.
      DEM Staff attended 3 days training program in Linux at the ELCOT Training Center-deputed from the University in the months of June and July, 2010.
    • Regular HIV/AIDS training programs are conducted in the Department for the Medical community since 1992.
    • EQAS (External Quality Assurance Scheme) training program is conducted biannually for Microbiologists and Laboratory technicians of Government Medical Colleges of Andhra Pradesh, Tamilnadu and Pondicherry since 2000 to bring qualitative improvement in the laboratories involved in HIV testing.
    • The Department conducted one-day training program "Training of Trainers (TOT) on Dried Blood Spots (DBS) collection in infant diagnosis of HIV by DNA PCR Test" on 21/09/07. This was in association with the Tamilnadu State AIDS Control Society and Clinton Foundation. This training was attended by Microbiologists and Pediatricians from 5 Government Medical Colleges of Tamilnadu. Subsequently Doctors, Laboratory Technicians and Nurses from Integrated Counselling Testing Centers(ICTC) and Antiretroviral Treatment (ART) centers of Tamilnadu and Tiruvallur districts were trained (in batches) in DBS collection in 2008 and 2009.
    • An "HIV Update" was conducted for 120 Medical Doctors of Tamilnadu on April 2008. Dr Ann J Melvin and Ms Nina Ellis from the University of Washington, Seattle delivered lectures. Dr Thor Wagner from University of Washington, Seattle,USA along with the Department faculty delivered lectures on Prevention of HIV/AIDS to the students of Vivekananda College of Arts and Science to commemorate World AIDS Day on December 1st 2007.
    • 10 days Residential Course on HIV/AIDS Clinical Management funded by AIDS Prevention And Control (APAC)- Voluntary Health Services VHS (USAID) was conducted at NamakkalGovernmentHospital. 212 doctors from Tamilnadu and Pondicherry were trained in 10 batches in the year 2006. Alumni meet was held on 21st May 2007 at Namakkal.
    • 3 days Doctors Training Program on HIV/AIDS was conducted in 2 batches at NamakkalGovernmentHospital for 50 doctors associated with Tamilnadu AIDS Initiative (TAI/VHS) in 2007.
    • The Medical Universities initiative to support the scaling up of ART in India –Certificate course was conducted in April 2004. 131 doctors from 3 Southern states of India & 4 International speakers participated. It was conducted in collaboration with 3 Medical Universities (TN. Dr. MGR Medical University, NTR University of Health Sciences-Andhra Pradesh, Rajiv Gandhi Institute of Health Sciences, Karnataka).
    • Structured Course on "Mother to Child Transmission of HIV" was conducted in Namakkal, August 2004. It was attended by 42 doctors and 27 nurses from the different states of India. Dr. Ann Melvin, Pediatrician from the University of Washington, Seattle was the international faculty.
    • The Department assisted in Counselling and HIV testing as part of Health Education program conducted at Kolli Hills, Namakkal in October 2004. The program was organized in the GovernmentHigh School. It was inaugurated by the District Collector Thiru.V.M. Xavier Chrisso Nayagam,. Dr. Saroja THADCO Chairman, Dr. C Velayutham, Deputy Director, Dr. G.Arunagiri Joint Director attended the program.
    • "Intercollegiate Freshers HIV/AIDS Awareness Workshop" was conducted on October 16th, 2004 at Nala Hotel, Namakkal. This workshop was organized by the Departmentinassociationwith Tamil Nadu State AIDS Control Society and Elizabeth Glaser Pediatric AIDS Foundation (EGPAF). 686 students from various Medical and Paramedical colleges around Namakkal participated in the workshop
    • Inter Collegiate Awareness workshop on HIV/AIDS was held on 29.11.04 at IMAGE auditorium, Chennai.1200 participants from the Medical and Paramedical colleges attended the workshop.
    • Inter Collegiate Awareness workshop on HIV/AIDS was held on 29.11.04 at IMAGE auditorium, Chennai.1200 participants from the Medical and Paramedical colleges attended the workshop.
    • A weeklong workshop on "Training of the Trainers in Counselling" was conducted in August 5-9th, 2003. NACO along with the Department and Tamil Nadu State AIDS Control Society had worked together to train 37 academicians and provided them 25 hours of Lecture along with interactive sessions and a visit to TB Sanatorium Hospital , Tambaram
    • The NICHD protocol training program was conducted from 17 Nov – 20th Dec 2003.The training program was attended by the Principal Investigators, Project Co-ordinators, Nurses, Counselors, Laboratory Technicians, Nutritionists and courier personal of the project. Pregnant women at Namakkal and RasipuramGovernmentHospitals were enrolled into the project from 30th December 2003.
    • First structured course on MTCT in India: Certificate Course on Mother to Child Transmission (of HIV) was conducted from March 25th -31st 2002. The course was designed to provide information and training of MTCT to Medical Doctors working with HIV/AIDS. 37 Pediatricians and Obstetricians from 8 states in India participated .Dr.Lisa Frenkel, Assistant Professor of Pediatrics and Laboratory Medicine from the University of Washington were the International Faculty for this course. The course was funded by the World AIDS Foundation.
    • In association with International AIDS Society (SHARE), 3 programs were conducted in 1999, 2002 and 2003 respectively. Satellite Symposia on "Management of HIV infected patients was conducted in 1999, "Antiretroviral Update" in 2002 and "Clinical management of HIV/AIDS for the Physicians" in 2003. Medical doctors from all over the country participated in these programs.
    • Training on MTCT was conducted in batches for 161 Village Health Nurses (VHN) at Namakkal district, September, 2000.
    • Training program on counseling and HIV testing was conducted in association with the National AIDS Control Organization for Microbiologists, Laboratory Technicians and Counsellors from GovernmentColleges and Hospital in South India, 1999
    • Round Table Conference on Prevention of HIV Transmission from mothers to infants –strategies for India. November 6th-8th, 1998 was conducted.
    • In association with Tamil Nadu State AIDS Control Society, HIV/AIDS Training was provided for 40 Microbiologists and 80 laboratory technicians in 6 batches, 1997.
    • International Conference on Challenge of Leptospirosis was conducted from September 8th-10th, 1997.
    • HIV update was conducted by the Department on February 5th, 1997.
    • "South Asian Workshop on Diagnostic Methods in Leptospirosis" (SAWDIL) was organized by the Department from January 9th-11th, 1995
    • Round Table Conference on AIDS Case Definition appropriate for India was held on July 29th and 30th, 1995.
    • Certificate Course on HIV/TB was conducted by the Department in Dec 11th-16th, 1994
    • Awareness programs on HIV/AIDS was conducted at Medical Schools both in City and rural areas, by public lectures and discussion in 1993.

    The following experts have provided lectures in the Department

    • Dr Hans Hager,Germany
    • Dr Joep Lange, Netherlands
    • Dr Elizabeth Dax, Australia
    • Dr Ann J Melvin, USA
    • Dr Lisa Frenkel, USA
    • Dr. Tim Mastro, USA
    • Dr Gareth Tudor Williams, UK
    • Dr Jennifer Read,USA
    • Dr Francoise Dabis, France
    • Dr. Michael Kazatskine, France
    • Dr. Wendy Holmes, Australia
    • Dr. Stefano Vella, Italy
    • Dr. Florence , Sweden
    • Dr. Wendy Holmes, Australia
    • Dr. Stefano Vella, Italy
    • Dr. Florence , Sweden
    • Dr. Hageman, Sweden
    • Dr Richard Portman, Netherlands
    • Ms. Amanda Murphy, UK
    • Dr. Koen Rompay, USA
    • Dr. Mark Weinberg, Canada

  • Journal Publications

    2012

    • Kalyanasundaram AP, Jacob SM, Hemalatha R, Sivakumar MR. Prevalence of Lipodystrophy and Dyslipidemia among Patients with HIV Infection on Generic ART in Rural South India. Journal of the International Association of Physicians in AIDS Care, 2012, 11(5): 329-334
    • Ragupathy V, Casado C, Jacob SM, Samuel NM, Lopez-Galindez C. Circulation of HIV-1 subtype A within the subtype C HIV-1 epidemic in Tamil Nadu, India. J Med Virol. 2012 Oct; 84(10):1507-13.
    • Dr. R. Viswanathan from FDA, Washington DC visited DEM on 6th &12 July, 2012 and discussed on the research aspects of HIV/AIDS.
    • Sushi KM, Thatchinamoorthy G, Jacob SM, Arumugam G, Anitha D. External Quality Assurance Scheme in a National Reference Laboratory for HIV Testing in South India. World Journal of AIDS, 2012, 2, 222-225
    • Jacob SM, Kalyanasundaram AP, Kumar ER, Durairaj A, Hemalatha R, Sivakumar MR. HIV-Lipodystrophy more Prevalent in Women than Men in Tamil Nadu, India. J AIDS Clinic Res 2012, 3 (3): 1000143
    • Uma KS, Jacob M, Arumugam G, Kalpana S, Natarajan MV. In vitro antimicrobial activity of the siddha drugs seenthil sarkarai and nilavembu kudineer against leptospira. Int J Pharm Pharm Sci, 2012, Vol 4, Suppl 2, 75-78.
    • Anitha D, Sumathi P, Mini Jacob S. Comparative study of venous liquid blood and dried blood for HIV infection in infants. International Journal of Biological and Medical Research, 2012, 3(1).

    2011

    • S. Jacob, K Annie Phoeb, R Hemalatha, MR Sivakumar. Age-specific prevalence of lipodystrophy among HIV positive individuals on ART in South India. (Abstract P-18) Reviews in antiviral therapy and infectious diseases journal 2011, 9: p 35
    • A. Kalyanasundaram, M Jacob, R Hemalatha, M R Sivakumar. Reproductive dysfunction associated with different age groups among HIV-infected individuals in rural South India. (Abstract P-02) Reviews in antiviral therapy and infectious diseases journal, 2011, 9: p22
    • D. Anitha, S Mini Jacob, A Ganesan, K Mary Sushi. Diagnosis of HIV-1 infection in infants using dried blood spots in Tamil Nadu,, South India. Indian Journal of Sexually Transmitted Diseases and AIDS. 2011; 32 (2): 99-102.
    • Mini S Jacob, Anitha Durairaj, James Vijayakumari, Parameshwari Srijayanth, MR Sivakumar. Detection of HIV drug resistance mutations in pregnant women receiving single dose Nevirapine in south India. Indian Journal of Pathology and Microbiology. 2011 Vol.54, Issue:2, pp359-361
    • Ganesan Arumugam, S Mini Jacob, D Anitha, Sivakumar Mampakkam Rajappa. Occurrence of leptospirosis among suspected cases in Chennai, Tamil Nadu. Indian Journal of Pathology and Microbiology 2011; 54(1): 100-102.

    2010

    • S Mini Jacob, K Annie Phoebe, R Hemalatha, MR Sivakumar, MP Ravindran, Adiponectin and Leptin levels in HIV Patients with lipodystrophy in Southern India. J Int AIDS Soc.2010; 13(Suppl 4): P75
    • Jennifer S. Read, MD, N. M. Samuel, Parameshwari Srijayanth, Shoba Dharmarajan, Hannah M. Van Hook, Mini Jacob, MD, Viju Junankar, James Bethel, Eunice Yu, MPH, and Sonia K. Stoszek. Infants of Human Immunodeficiency Virus Type 1-Infected Women in Rural South India: Feeding Patterns and Risk of Mother-to-Child Transmission. The Pediatric Infectious Disease Journal. Volume 29, Number 1, January 2010: 14-17.
    • Sivakumar M. R, Sanath Kumar J, Viswanath R, Thatchinamoorthy G, Mini Jacob & Samuel N M. Western blot pattern in HIV positive individuals in Namakkal, South India. The Internet Journal of Infectious Diseases.2008 Volume 6 Number 2
    • Srijayanth Parameshwari, Mini S Jacob, JJ Vijaykumari, Diana Shalini, Mary Sushi, Sivakumar MR. A program on prevention of mother to child transmission of HIV at government hospital, Tiruchengode taluk, Namakkal district. Indian Journal of Community Medicine, Volume 34, Issue 3, July 2009: 261-263
    • Radhakrishnan R, Samuel NM, Mini Jacob S, Murthy B.N, Parameshwari S, Kavitha D, Hans Jager. Transmission of Cell free (CFV) HIV-1 RNA through breast feeding: a pilot study in Chennai-India. Libyan Journal of Infectious Diseases. Vol 3 No.1 January 2009: 37-43
    • Mini Jacob S , Anitha D , Vishwanath R , Parameshwari S , Samuel NM. The use of dried blood spots on filter paper for the diagnosis of HIV-1 in infants born to HIV seropositive women. (Indian J Med Microbiol. 2008 Jan-Mar; 26(1): 71-74.
    • Ingrid A Beck, Claudia Crowell, Robin Kittoe, Helba Bredell, Molefe Machaba, Carolyn Willamson, Wouter Janssens, Sabelle Jallow, Guindo van der Groen, Yiming Shao, Mini Jacob, N.M.Samuel, Ivette Lorenzana de Rivera, Nicole Ngo-Giang-Huang, Sharon Cassol, Geprge Alemnji, Lisa M Frenkel. Optimzation of the Oligonucleotide Ligation Assay, a rapid and inexpensive test for detection of HIV-1 Drug resistance mutations for Non-North American Variants. J Acqir Immuno Defic Syndr. Volume 48, No.4, August 1, 2008: 418-427
    • Annie Phoebe K, Mini Jacob, Samuel NM, Sivakumar M.R., Meer Mustafa Hussain K. Serum Leptin Levels and Metabolic Alterations in HIV- infected Antiretroviral-naïve Individuals in South India. Reviews in Antiviral Therapy 2008 volume 4, page 34.
    • Samuel N.M, P. Srijayanth, S. Dharmarajan, J. Bethel, H. Van Hook, M. Jacob, V. Junankar J. Chamberlin, D. Collins & J.S. Read. Acceptance of HIV-1 education & voluntary counselling/testing by & seroprevalence of HIV-1 among, pregnant women in rural south India. Indian Journal of Medical Research 125, January 2007, pp 49-64.
    • Jennifer S. Read, N.M. Samuel, S. Parameshwari, Shoba Dharmarajan, Hannah M. Van Hook, S. Mini Jacob, Viju Junankar, James Bethel, Jiahong Xu, and Sonia K. Stoszek Safety of HIV-1 Perinatal Transmission Prophylaxis With Zidovudine and Nevirapine in Rural South India. Journal of International Association of Physicians on AIDS Care (Chic Ill) 2007 6: 125-136
    • Deepti Gupta, Dekey Lhewa, R. Viswanath, S. Mini Jacob, S. Parameshwari, R. Radhakrishnan, Kristy Seidel, Lisa M. Frenkel, NM Samuel, and Ann J. Melvin. Effectiveness of antenatal group HIV voluntary counseling and testing services in rural India. AIDS Education and Prevention, 19(3), 187–197, 2007.
    • Samuel N M, Mini Jacob, Ravichandran R, Muthusethupathi MA, Sundari V G "Prevalence of HIV infection among renal transplant patients in Madras, India." Journal of Association of Physicians of India. Volume 44 May 1996 Page 358.

    Abstract Publications

    • Ganesan A, Anitha D, Jacob Mini, Sivakumar.M.R. and Meer Mustafa Hussain K
    • "Leptospirosis coinfection among HIV infected patients in Chennai, India." 5th IAS
    • Conference on HIV Pathogenesis Treatment and Prevention 19-22nd July 2009, Cape Town, South Africa. 2009. Abstract No. A-155-0067-02856
    • E Ramesh Kumar, R Ravikumar, Jagadeesan, Mini Jacob, Parameshwari, NM Samuel. The Efficacy and adverse effects of combination of stavudine/lamivudine/nevirapine among adult HIV patients in Namakkal, Tamilnadu. International Conference on Opportunistic Pathogens in AIDS. Conference Proceedings. January 27-29, New Delhi, 2008, No.16, p175.
    • Lipid profile alternations in HIV Infected antitetroviral-naïve individuals. Annie Phoebe K, Mini Jacob, Vijayakumari JJ, Ganesan A, Samuel NM. International Conference on Opportunistic Pathogens in AIDS. Conference Proceedings. January 27-29, New Delhi, 2008, No.09, p172.
    • Mini Jacob, Anitha D, Viswanath R, Ganesan A, Parameshwari S. Feasibility of using DNA PCR on Dried Blood Spots for diagnosis of HIV-1 in infants in a PMTCT program in South India. International Conference on Opportunistic Pathogens in AIDS. Conference Proceedings. January 27-29, New Delhi, 2008, PP-08, p150.
    • Thilagavathy Chinnusamy, Antony Jennit, Vijayakumari JJ, Parameshwari S, Mini Jacob, Samuel NM. Outcome of the lower segment caesarian section (LSCS) in HIV positive women at DistrictHeadQuarterHospital, Namakkal. International Conference on Opportunistic Pathogens in AIDS. Conference Proceedings. January 27-29, New Delhi, 2008, OP-15, p137.
    • S.Parameshwari, S.Mini Jacob, JJ.Vijayakumari., Antony Jennit., NM.Samuel, MR.Sivakumar, K.Meer Mustafa Hussain. Prevention of Mother To Child Transmission of HIV Program in Rural South India (ANC as a Entry Point). HIV Congress 2008 March 21st -23rd Mumbai, India
    • Sivakumar. M.R., Sanath Kumar J, Viswanath R, Thatchinamoorthy G, Mini Jacob, NM. Samuel, Meer Mustafa Hussain. K. Western Blot Pattern in HIV Positive Individuals in Namakkal, South India. HIV Congress 2008 March 21st -23rd Mumbai, India
    • Ganesan A, Anitha D, Jacob Mini, Parameswari S, Sivakumar M.R., Meer Mustafa Hussain. K. Leptospira Infection in Seropositive HIV Subjects in Chennai, South India. HIV Congress 2008 March 21st -23rd, Mumbai, India.
    • Mini Jacob, Anitha D, JJ Vijayakumari, Parameshwari, Ann Melvin, Lisa Frenkel, Samuel NM Detection of the onset of drug resistant mutations in pregnant women receiving single dose Nevirapine in Namakkal, Tamilnadu, using Oligonucleotide Ligation Assay.4th IAS Conference on HIV Pathogenesis, Treatment and Prevention. 22-25th July 2007, Sidney, Australia. Abstract No. TUPEB035
    • Mini Jacob, Parameshwari Srijayanth, Shoba Dharmarajan, NM Samuel, Doreen Collins, Sonia Stoszek, Viju Junankar, James Bethel, Jennifer S Read. Severe neutropenia among HIV-1-exposed infants according to maternal antiretroviral prophylaxis regimen. Eighth International Congress on Drug Therapy in HIV Infection 12-16 November 2006 Glasgow, UK. Abstract No. P386.
    • Shoba Dharmarajan, NM Samuel, Parameshwari Srijayanth, James Bethel, Hannah Vanhook, Mini Jacob, Viju Junankar, Doreen Collin, Jennifer Read. Hemoglobin among HIV-1-infected pregnant women in rural India according to antiretroviral prophylaxis regimens. Eighth International Congress on Drug Therapy in HIV Infection 12-16 November 2006 Glasgow, UK. Abstract No. P384
    • R Radhakrishnan, S Mini Jacob, S Kavitha Daniel, NM Samuel. Transmission of cell free HIV-1 RNA through breast feeding: a pilot study in Chennai, India. Eighth International Congress on Drug Therapy in HIV Infection 12-16 November 2006 Glasgow, UK. Abstract No. P375
    • B J Srihari, Mini Jacob S, Sunderavalli A, Lakshmi Devi R, Murthy BM, Bhirmanandham CV, Samuel NM. Maternal CD4 T cell counts, viral load and subtype in association with HIV-1 perinatal transmission. . 3rd IAS Conference on HIV Pathogenesis and Treatment. Rio de Janeiro. 2005
    • Vijayakumari J., Rukmani R., Anuradha G., Jacob M., Srijeyanth P., Samuel N.M. Discordant couples among HIV positive pregnant women in PMTCT Program. 3rd IAS Conference on HIV Pathogenesis and Treatment. Rio de Janeiro. 2005 (Abstract No.TuOa0305)
    • Dharmarajan S, Srijayanth P, Read J, Samuel N, Jacob M, Van Hook H, Elango R, Collind D, Junankar V, Bethel J. "Risk factors for HIV-1 seropositivity among pregnant women in rural Tamilnadu, India". The 3rd IAS Conference on HIV Pathogenesis and Treatment, Rio de Janeiro, Brazil, 24-27th July, 2005 Abstract No TuPe5.IP05
    • Srijayanth P, Dharmarajan S, Read J, Jacob M, Samuel N, Elango R, Junankar V, Collins D, Van Hook H, Bethel J. "Baseline Knowledge regarding HIV infection and Transmission among pregnant women in Rural Tamilnadu, India" The 3rd IAS Conference on HIV Pathogenesis and Treatment, Rio de Janeiro, Brazil, 24-27th July, 2005. Abstract No.TuPe5.5P13
    • Dharmarajan S, Srijayanth P, Samuel N, Collins D, Van Hook H, Elango R, Jacob M, Jaunakar V, Bethel J, Read J "Acceptability of enrollment into a prospective cohort study and of a more complex antiretroviral prophylaxis regimen: Operational Research in Rural India" The 3rd IAS Conference on HIV Pathogenesis and Treatment, Rio de Janeiro, Brazil, 24-27th July, 2005. Abstract No.MoPe11.7C04
    • Jennifer S Read MD MPH, NM Samuel MBBS, PHD, Parameshwari Srijayanth MBBS, Hannah Van Hook BS, Shoba Dharmarajan MBBS, Mini Jacob MBBS MD, Viju Junankar BS, James Bethel PHD. "HIV infection among pregnant women in rural Tamilnadu, India" IDSA, Boston, 2004
    • G Thatchinamoorthy, S Ruckmani, S M Jacob " Infections waste disposal, infection control strategies and needle stick injuries in a rural clinical setting" The XV International AIDS Conference 2004 July 11;6(3);B11840 [eJIAS, 2004 Jul11;1(1):B11840]
    • K Mary Sushi, S Mini Jacob, R Viswanath, S Parameshwari, N M Samuel "External Quality assurance in voluntary counseling & testing centres in Southern India" The XV International AIDS Conference 2004 July 11;6(3);B11136 [eJIAS, 2004 Jul11;1(1):B11136]
    • S M Jacob, S Parameshwari, N M Samuel " Implementation of HIV mother-to-child transmission prevention program in a Primary Health Center in India" The XV International AIDS Conference 2004 July 11;6(3);E12214 [eJIAS, 2004 Jul11;1(1):E12214]
    • R Radhakrishnan, S Mini Jacob, S Parameshwari, R Rukmani, N M Samuel " Infant feeding practices and its effect on infants born to HIV seropositive women – Tamilnadu, India" The XV International AIDS Conference 2004 July 11;6(3);B11912 [eJIAS, 2004 Jul11;1(1):B11912]
    • D Shoba, S Parameshwari, S M Jacob, N M Samuel " Follow up of children of HIV seropositive women from a cohort in rural South India – A Clinical report" The XV International AIDS Conference 2004 July 11;6(3);B12580 [eJIAS, 2004 Jul11;1(1):B12580]
    • R Viswanath, S Mini Jacob, N M Samuel "HIV-1 subtypes circulate in South India "The XV International AIDS Conference 2004 July 11;6(3);A10245 [eJIAS, 2004 Jul11;1(1):A10245]
    • S Parameshwari, J Saramini, K Mary Sushi, N M Samuel "Detection of discordant couples in a routine PMTCT clinic in India The XV International AIDS Conference 2004 July 11;6(3);B11112 [eJIAS, 2004 Jul11;1(1):B11112]
    • B J Srihari, S M Jacob, A Sundaravalli, B Lakshmi Devi, N M Samuel "HIV-1 subtype in relation to perinatal transmission among seropositive pregnant women of South India The XV International AIDS Conference 2004 July 11;6(3);C12676 [eJIAS, 2004 Jul11;1(1):C12676]
    • P Srijanth, N M Samuel, J S Read, J Bethel, S Dharmarajan, J Chamberlin, S M Jacob, H Van Hook "Knowledge, attitudes and beliefs regarding HIV among pregnant women in rural Tamilnadu, India" The XV International AIDS Conference 2004 July 11;6(3);B11464 [eJIAS, 2004 Jul11;1(1):B11464]
    • J J Vijayakumrai, J Sara Mini, N M Samuel "Challenges encountered in administering the second dose Nevirapine to the infants born to HIV positive women in Namakkal PMTCT Project, India" The XV International AIDS Conference 2004 July 11;6(3);ThPeB7034 [eJIAS, 2004 Jul11;1(1):ThPeB7034]
    • J S Read, N M Samuel , P Srijayanth, H Van Hook, S Dharmarajan, S M Jacob, V Junankar, J Bethel "Seroprevalence of HIV infection among pregnant women in rural Tamilnadu, India" The XV International AIDS Conference 2004 July 11;6(3);ThPeC7300 [eJIAS, 2004 Jul11;1(1):ThPeC7300]
    • D Anitha, R Viswanath, S M Jacob, N M Samuel "Cost effective HIV DNA PCR using dried blood spots in resource constrained settings" The XV International AIDS Conference 2004 July 11;6(3);WePpB2058 [eJIAS, 2004 Jul 11;1(1):WePpB2058
    • NM Samuel, S Mini Jacob, S Parameshwari, R Vishwanathan, CV Bhirmanandham, G Arunagiri, JJ Vijayakumari, K Dheenabandhu "Prevention of mother to infant programme in Rural India has facilitated HIV Prevention, ART and Care of the infected". The XV International AIDS Conference 2004 July 11;6(3);ThPeB7078 [eJIAS, 2004 Jul11;1(1):ThPeB7078]
    • D Anitha, R Vishwanath, SM Jacob and NM Samuel "Detection of Chlamydia Trachomatis and Neisseria Gonorrhoea in pooled urine samples by Multiplex PCR" The 2nd IAS Conference on HIV Pathogenesis and Treatment, Paris, France, 13-16th July, 2003. Abstract No.1277 page S532.
    • R Radhakrishnan, S Mini Jacob, S Parameshwari, CV Bhirmanandham and NM Samuel "Exclusive breastfeeding practices: A myth or reality" The 2nd IAS Conference on HIV Pathogenesis and Treatment, Paris, France, 13-16th July, 2003. Abstract No.1066 page S486.
    • BJ Srihari, M Jacob, S Rajasekaran, VC Bhirmanandham and NM Samuel "Correlation of CD4 T cells with Total Lymphocyte Counts (TLC)- A marker for monitoring HIV/AIDS patients in resource limited settings" The 2nd IAS Conference on HIV Pathogenesis and Treatment, Paris, France, 13-16th July, 2003. Abstract No.477 page S310
    • Parameshwari S, Vijayakumari J, Mini Jacob, Viswanath R, Anitha D and Samuel NM "Nevirapine In unregistered Seropositive mother at Namakkal government hospital in south India" 14th international AIDS conference, Barcelona, July 2002.
    • Mary Sushi K, Mini Jacob, Parameshwari S, Vishwanath R, Samuel N M "Importance of External Quality control scheme in HIV testing in Resource limited setting in India" 14th international AIDS conference, Barcelona, July 2002.
    • Mini Jacob, Parameshwari S, Vishwanath R, Sushi M, Samuel NM "Impact of HIV/AIDS education among students in rural Tamilnadu, India" 14th international AIDS conference, Barcelona, July 2002.
    • Radhakrishnan, , Mini Jacob, Parameshwari S, Vishwanath R, Mary K, Anitha D, Samuel N M-"Breast feeding a marker for discrimination in HIV positive mothers"- 14th international AIDS conference, Barcelona, July 2002.
    • Viswanath R, Mini Jacob S, Shaffi Ahamed S, Joshi PL and Samuel N M- "Qualitative DNA PCR for HIV-1 diagnosis in Infants" 14th international AIDS conference, Barcelona, July 2002.
    • Samuel N M, Parameshwari S, Mini Jacob S, Hari B, Vishwanath R, " Assessing intervention to reduce vertical transmission of HIV in Namakkal – rural hospital in south India"- 1st IAS conference on HIV pathogenesis and treatment 2001" No.756 (page 308)
    • Mini Jacob S, Parameshwari S, Mary Sushi K, Viswanath R, Anitha S, Samuel N M- "Is Viral load essential for ARV"- 3rd International conference on AIDS India 2000, Chennai, December 2001.
    • Mini Jacob S, Radhakrishnan, Parameshwari S, Samuel N M. "Breast feeding pattern in Tamilnadu"- 3rd International Conference on AIDS India 2000, Chennai, December 2001.
    • Radhakrishnan, Parameshwari S, Mini JacobS, Samuel N M. "Breast feeding a marker for discrimination in HIV positive mothers"- 3rd International conference on AIDS India 2000, Chennai, December 2001.
    • Srihari B J, Mini JacobS, Parameshwari S, Tripathy S P, Samuel N M "HIV-1 subtypes circulating in Namakkal, Tamilnadu"-3rd International Conference on AIDS India 2000, Chennai, December 2001.
    • Samuel N M, Parameshwari, Mini Jacob S, Viswanath R "Assessing intervention to reduce vertical transmission of HIV in Namakkal – rural hospital in South India"- 1st IAS conference on HIV pathogenesis and treatment 2001" No 891
    • Dr. Tim Mastro, USA
    • Parameshwari S, Samuel N M, Mini Jacob S-"MTCT training (VHN) in Namakkal District"-3rd conference on Global Strategies 2001.
    • Mini Jacob S, Parameshwari S, Samuel N M "To use HIV rapid test in pregnant women attending Namakkal Government Hospital in South India". 3rd Conference on Global Strategies, Uganda 2001.
    • Parameshwari S, Mini Jacob, Viswanath R, Vijayakumari V, Samuel N M, Uma Maheswari, Uma P, Thirumozhi K- "MTCT prevention center in Namakkal"- 3rd International conference on AIDS India 2000, Chennai, December 2001.
    • Mary Sushi K, Parameswari S, Mini Jacob S, Anandakannan K, Samuel N M. Problems encountered in working with seropositive pregnant mothers. IInd International Confernce on AIDS INDIA 2000, Chennai 1999
    • Alamelu C, Jagganath, Anandakannan K, Samuel N M Diagnostic Value of measuring IgG antibody to Lipo arabinomannan (LAM) Antigen in patients with pulmonary Tuberculosis. IInd International Conference on AIDS INDIA 2000, Chennai 1999
    • Parameswari S, Mallika K, Mini Jacob S, Anandakannan K, Samuel N M Administration of AZT to Unregistered Mothers prior to Caesarean section. IInd International Conference on AIDS INDIA 2000, Chennai 1999
    • Mini JacobS, Mary Sushi K, Parameswari S, Umayal, Anandakannan K ,Samuel N M Potential Benefits of Pooled sera technique in screening of HIV. IInd International Conference on AIDS INDIA 2000 Chennai 1999
    • Jacob Mini S , Mary Sushi K, Parameswari S, Umayal, Ananda Kannan, Samuel N M "Potential benefits of pooled sera technique in screening of HIV" 2nd International Conference on AIDS India 2000, Chennai, December 1999.
    • Samuel N M, S Parameshwari, Mini Jacob, H Geiger, B Naidoo, Raja D "Immunological and virological analysis of a triple combination pilot study and traditional drugs in HIV infected patients in South India". 12th World AIDS Conference, Geneva July 1998.
    • Samuel N M, S Parameshwari, Amanda Murphy, Mini Jacob S, Hans Gager, D Raja "Evaluation of the efficacy and tolerance of AZT and Lamivudine in South Indian HIV infected patients". 12th World AIDS Conference, Geneva, Switzerland July 1998.
    • Mini Jacob, Samuel N.M. HIV Infection in Renal Transplant Recepients in South India. 12th world AIDS Conference Geneva 1998
    • Parameswari S, Rita Padmini, Samuel N M. Cervical Biopsy analysis in women with HIV infection. 12th World AIDS Confernce Geneva, 1998
    • Parameswari S, Samuel N M. Results of Observational Study at Chennai, Modified ACTG 076. Perinatal Confernce, Chennai 1998
    • Viswanath R, Raja D, Samuel N M. CD4/CD8 Profile of Normals and petients with TB, HIV/TB, HIV/AIDS in South India. The International Journal of Tuberculosis and Lund Diseases Vol.2, No.11, Nov 1998
    • Jacob Mini S, Sundari V G, Ravichandran R, Muthusethupathi M A, Raja D, Samuel N M " Measurement of cyclosporine trough level in Indian Renal Transplant patients by High Pressure Liquid Chromatography". IX annual conference of Indian Organ Transplantation 10-12th January 1997.
    • Samuel N M, Viswanath R, Parameswari S, Olaleya & DietrichU. The Emerging Diversity of HIV-1 in South India. First International Conference on AIDS INDIA 2000, 1997
    • Kalpana S, Jeyakar Paul, Deivanayagam C N, Raja D , Samuel N M. Prevalence of HIV-2 Infection in South India. First International Conference on AIDS INDIA 2000 1997
    • Viswanath R, Deivanayagam C N, Sankaran J R, Samuel N M. Enumeration of CD4/CD8 cell counts in patients with HIV/AIDS, HIV /STD, HIV/TB in Tamilnadu. First International Conference on AIDS INDIA 2000 1997
    • Mini Jacob, Ravichandran R, Raja D, Sundari V G, Samuel N M. HIV in Renal Transplant patients - South Indian perspective. First International Conference on AIDS INDIA 2000 1997
    • Parameswari S, Raja D, Samuel N M. Indian Experience of Administration of Zidovudine to HIV seropositive mothers and Infants. First International Conference on AIDS INDIA 2000 1997
    • Adeline Francis, Vijayasekaran, Alamelu Chandrasekaran, Raja D, Samuel N M. Detection of Tuberculosis by DNA Amplification in Lympphnodes in children. First International Conference on AIDS INDIA 2000 1997
    • Samuel N M, Parameswari S, Mini Jacob, Adeline Francis, Brian Naidoo. HIV RNA Quantitation in periperal Blood. First International Confernce on AIDS INDIA 2000, 1997
    • Viswanath R, Samuel N M .Estimation of Chlorine content in drinking water and test for Leptospira contamination. Challenge in Leptospirosis 1997
    • Parameswari S, Shanmugapriya A, Samuel N M. Anonymous Unlinked Screening of HIV Infection in pregnant women. IAMM XX National Congress, Agra 1996
    • Viswanath R, Kalpana S, Samuel N M. Is Blood Safe. IAMM XX National Congress, Agra 1996
    • Mini Jacob S, Chandrasekharan S, Samuel N M Vitamin A analysis in Normal Children and Children with Tuberculosis. IAMM XX National Congress Agra 1996
    • Kalpana S, Samuel N M. Serodiagnosis of Leptospirosis by Microscopic Agglutination test. IAMM XX National Congress Agra 1996
    • Samuel N M, Parameswari S, Swarnakumari . Zidovudine in HIV postive pregnant women and their babies. National Medical Journal of India, Vol.9, No.4, 1996

  • Ongoing Research Projects

    • Indo US Collaborative project on: Reservoirs of drug resistant HIV-1: Impact of drug resistance HIV-1 reservoirs on efficacy of childhood ART (Funded by ICMR)
    • HIV DNA PCR using gag primers versus envelope primers
    • Standardization of HLA B5701 for Abacavir hypersensitivity
    • Biochemical and Immunological parameters in HIV patients
    • The role of placenta in transmission of HIV from mothers to infants.
    • iral loads in HIV patients on Homeopathic treatment (in collaboration with Clinical Research Unit of Homeopathy, MMC)
    • The role of placenta in transmission of HIV from mothers to infants.

    Completed projects

    • To evaluate the onset of Drug resistance mutations (using Oligonucleotide Ligase Assay) in women receiving single dose Nevirapine in Tamil Nadu, South India
    • Pap Smear abnormalities in HIV positive women in Namakkal
    • Lipid abnormalities in HIV positive individuals who have received HAART for more than one year in Namakkal District
    • Genetic variability of HIV in India
    • HIV transmission through breast milk.
    • HIV-1 Viral Dynamics in seropositive pregnant women in relation to perinatal transmission
    • A prospective cohort study of the seroprevalence of and intervention to decrease the risk of mother to child transmission of Human Immunodeficiency Virus Type 1 (HIV) in Tamil Nadu, India.
    • The infant feeding patterns practiced by HIV seropositive mother
    • Pilot study to evaluate efficacy tolerance and adherence of three antiretrovirals drug regimen in resource constrained rural district of Namakkal in South India.
    • A study of stigma attached to HIV infection implications for health care and social adjustment.
    • A study of impact of counseling on coping behavior of HIV positive cases in different states.
    • Detection of Chlamydia Trachomatis and Neisseria Gonorrhea in pooled urine samples by Multiplex PCR – Community based study
    • Prevalence of Hepatitis B and Hepatitis C among HIV seropositive antenatal women in two hospitals of Tamil Nadu
    • Diagnosis of HIV infection in infants using dried blood spots for HIV DNA PCR
    • Study to evaluate efficacy, tolerance and adherance of three antiretroviral drug regimen in resource constrained rural district of Namakkal in South India.
    • Specific alternative monitoring and evaluation tools of ARV therapy in resource limited settings
    • Combination of antiretrovirals in sero positive pregnant women for reduction of MTCT.
    • Seroprevalence of HIV in STD patients, blood donors and tuberculosis patients
    • Estimation of CD4/CD8 lymphocyte counts in South Indian Normals, HIV patients.
    • Prevalence of Hepatitis B and Hepatitis C among HIV seropositive antenatal women in two hospitals of Tamil Nadu
    • HIVV/TB patients and tuberculosis patients.
    • Seroprevalence of HTLV in South Indian blood donors
    • Leptospira antibody in normal individuals of Chennai city and sewage workers
    • Prevalence of HIV infection among renal transplant patients in Chennai
    • HIV prevalence in antenatal women, destitute and mentally retarded women and women who frequent an abortion clinic.
    • Detection of HIV antibodies in Serum, Saliva and Crevicular fluid
    • Estimation of trace metal levels in serum and saliva of HIV patients and controls
    • HIV seroprevalence in malnourished children and estimation of trace elements in them
    • Detection of antibodies to HIV in paired serum and urine
    • Cervical biopsy analysis in women with HIV infection
    • Health Survey of Udavum Karangal, an orphanage in Chennai
    • Comparison of MSAT and MAT in the diagnosis of Leptospirosis
    • Estimation of CD4/CD8 lymphocyte counts in South Indian Normals, HIV patients.
    • Validation of HIV rapid test kits for screening, surveillance & diagnosis in voluntary testing & counselling centers.
    • Diagnosis of Tuberculosis by DNA amplification in the lymph nodes of children
    • Correlation of CD4 T Cells with Total Lymphocyte Count (TLC)- a marker for monitoring HIV/AIDS patients in resource-limited settings

  • Diagnostic Services offered by the Department
    HIV/AIDS Tests * Charges
    Rapid Rs. 100 (result in 1 day)
    ELISA Rs. 100 (result in 3 days)
    Western Blot Rs. 1200 (result in 3 days)
    CD4/CD8 counts Rs. 1000 (result in 1 day)
    Viral Load Rs. 3,500 (result in 7 days)
    Qualitative DNA PCR Rs. 800 (result in 7 days)
    Subject to the availability of kits.
    Leptospira Diagnostic Test Charges
    Microscopic Agglutination Test (MAT) & Dark Field Microscopy Rs.250 (same day result or next day )
    Tests (Using rapid test kits)
    Name of the Test Charges
    Dengue Rs. 200 (results on the same day)
    Widel Rs. 200 (results on the same day)
    Tests available for Research Programs
    P24 antigen test
    DNA PCR using Dried Blood Spots (DBS)
    PCR for Leptospirosis
    Sequencing for HIV
    HLA-B5701
    PCR for Human Papilloma Virus
    Human Simplex Virus using ELISA and Western Blot.
    Cryptococcal antigen tests using latex agglutination kit

  • National

    • Memorandum of Understanding (MoU) was signed between Tamilnadu AIDS Initiative and Tamilnadu Dr MGR Medical University for training the Medical Doctors (attached to the TAI/VHS) on HIV/AIDS Clinical Management in 2006
    • HIV/AIDS clinical Management residential course in collaboration with APAC-VHS (USAID) in 2006
    • The Department collaborates with the following agencies for various HIV/AIDS Programs
      • Tamil Nadu State AIDS Control Society (TANSAC),
      • National AIDS Control Society (NACO)
      • Indian Council Of Medical Research (ICMR)
      • Indian Council Of Medical Research (ICMR)
      • National Institute of Epidemiology (NIE), Chennai
      • National AIDS Research Institute (NARI), Pune
      • Namakkal Head Quarters Hospital

    International

    • In August 2004, MoU was signed between TN Dr.MGR Medical University and University of Washington., Seattle.USA. This collaboration affirms interchange of students, faculty and staff. Staff members of the Department have been trained in HIV laboratory and Medical students from University of Washington have visited the University and Namakkal PMTCT programs. This interchange has lead to several research publications (2004-2009)
    • Memorandum of Understanding was signed between National Institute of Child Health and Human Development (NICHD), USA and The Tamilnadu Dr. M.G.R. Medical University. The collaborative project (2003-2006) is on "A prospective Cohort study of the seroprevalence of and Intervention to decrease the risk of Mother to Child Transmission of Human Immuno deficiency Virus type 1 (HIV) in Tamilnadu, India". Zidovudine is provided for HIV positive mothers and Zidovudine syrup to the infants
    • The University is collaborating with Elizabeth Glaser Pediatric AIDS Foundation, USA since 2002 in providing care and support to women and infants with HIV/AIDS.
    • In 2005, MoU has been signed with Lund University, Sweden for conducting HIV/AIDS research.

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